Stephen, welcome to the registered fold
First, yes, Pluto is within a degree of MC in that Ennead - in fact, for central coordinates in Manila, it's only 0°09' away. Uranus is less than 5° below Asc, which isn't nearly as strong, but is nonetheless worth noting, especially for it's similarity to Pluto. Probably most important of all, natal Jupiter is about a degree from opposition to transiting Pluto.
To put this in perspective and allay some anxiety, Pluto on an angle happens all the time. You've had it hundreds of times in your life. For a conservative 3° orb, every planet (on average) is angular about 10% of the time, so of the 3,400 or so lunars, demi-lunars, Enneads, and decilia you've had in your life, every planet has been on an angle about 340 times.
The unique thing at the moment, is Pluto's transit to Jupiter, which first enters a 1° roughly the day of the Ennead and will last leave that orb in December 2023 - so, basically this year and next year. I'll be going through this with you, since my Jupiter is only 0°07' from your Jupiter (though I also have Uranus there). Like me, you've probably already had this foreground in numerous returns, but now it takes center stage for a while.
You can read a standard interpretation of this transit on this page:
viewtopic.php?f=24&t=239&p=1616#p1617
The simple meaning is that these two years, in some important ways, will redefine the Jupiter area of your life, signaling major shifts in such things as status, finances, reputation, and ethics. Most of the time this is felt as a positive aspect, a real move forward. That is, in
theory it can be positive or negative - can be elevation and promotion on the one hand or dragging down the mighty - but most of the time it is positive. Consider that Donald Trump had this transit for most of his presidency and, while he faced impeachment twice (unprecedented), he also skated free of it due to almost inconceivable protection. Joe Biden then beat Trump in the last election under the same transit and continues to have strong effects from the transit; but Biden's
strongest effects of the transit were during the months he was rolling out almost unprecedented programs, his months of greatest success and accomplishment. (His recent drop in the polls coincided with the time the Pluto transit has pulled out of close orb.)
The exact form all this takes depends on the condition of your life, occupation, finances, and other factors. It's a good time to read (or re-read) the
Tao Teh Ching and its lessons of the rhythmic uplifting of the small and dragging down of the too-mighty, plus its larger message of all phenomena being in ongoing change.
While all of this is going on this year and next, you will have some periods of poorer transits and some periods of excellent ones. Right now, Jupiter is opposing your Venus, soon to oppose your Moon - which are as fine a pair of transits as one could want. Through most of February, transiting Jupiter will be crossing your natal angles. In March and April, with Pluto only minutes from opposite your Jupiter, Jupiter will oppose your Pluto - and your Uranus and Sun, quite changing the feel of the Neptune to natal Sun (etc.) you've been going through.
In fact, I suspect that's the root of your anxiety: You've been under a lot of Neptune for a year or more and, recently, Saturn opposite your Mars. (And I just saw that you're in a two-month progressed Moon-Mars conjunction.) Maybe you have some wounds to lick, or at least some doubts to assuage. In April, this tone of the Neptune transit will switch to the inflating optimism of Jupiter-Neptune to Sun and other planets.
Meanwhile, progressed Moon is in the last third of Leo, going across your late-Leo planets. A likely decisive shift will occur as progressed Moon crosses your Pluto and Uranus in March-May, climaxing close to May 5. I'm not sure what will happen then, but it likely will be a significant shift. Progressed Moon conjoins your Sun May 18, often a significant turning point in life - usually positive (but some circumstances need to rearrange to make room for that). Think back 27 years for what happened - the last couple of months of 1994 through January '95, more or less - for analogies of what to expect now.
According to progressions, October will be the worst month of the year as progressed Moon opposes Saturn. (Moon opposes
progressed Saturn the last half of July.
All of this is under the big umbrella of your current solar return, which is a neutral-themed chart, primarily marked by Mercury on Ascendant. SSR Moon squares your natal cluster of Sun-Mercury-Uranus-Pluto, so you're already in a transition cycle with things moving around in your life most likely. Thed worst time of the solar return year was likely four months after your birthday - this last month (early January) - as progressed SSR Moon squared when you were already having a Moon-Mars progression. Were December-January pretty hard on you?